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Related Experiment Videos

Multiphase hepatic CT with a multirow detector CT scanner.

W D Foley1, T A Mallisee, M D Hohenwalter

  • 1Department of Radiology, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226, USA.

AJR. American Journal of Roentgenology
|August 23, 2000
PubMed
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This study introduces a new CT scan technique to separate liver blood flow into three phases. This method optimizes detection of hypervascular tumors in both cirrhotic and non-cirrhotic patients.

Area of Science:

  • Radiology
  • Medical Imaging
  • Hepatobiliary Imaging

Background:

  • Hypervascular neoplasms in the liver require precise imaging for early detection.
  • Current CT techniques may not optimally delineate distinct hepatic circulatory phases for tumor contrast.

Purpose of the Study:

  • To evaluate a novel multirow detector CT (MDCT) injection-acquisition technique for separating hepatic artery, portal venous inflow, and hepatic venous phases.
  • To determine the optimal hepatic phase for detecting hypervascular neoplasms.

Main Methods:

  • A new MDCT technique was used with sequential acquisitions during a single breath-hold.
  • Circulation time was determined by a preliminary mini-bolus, followed by two main acquisitions.
  • Tumor-to-liver contrast was evaluated in cirrhotic and non-cirrhotic patients with hypervascular neoplasms.

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Main Results:

  • Three distinct hepatic circulatory phases (hepatic artery, portal venous inflow, hepatic venous) were successfully visualized.
  • Maximum tumor-to-liver contrast for hypervascular neoplasms occurred during the second acquisition phase (portal venous inflow/late arterial).
  • Three-dimensional CT arteriograms were obtained, clearly showing hepatic vessels.

Conclusions:

  • Rapid-sequence hepatic helical CT enables optimal timing for hypervascular tumor detection.
  • A new paradigm of three distinct hepatic phases (arterial, portal venous inflow, hepatic venous) is recommended for enhanced detection.
  • This technique improves the detection of hypervascular liver tumors.