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[Aminoglycoside antibiotics from clinical viewpoint]
International Journal of Clinical Pharmacology and Biopharmacy
|March 1, 1975
Summary
This review details the indications, side effects, dosage, and pharmacokinetics of key aminoglycoside antibiotics like gentamicin and amikacin. It also covers antibiotic combinations and therapeutic drug monitoring of aminoglycoside serum concentrations.
Area of Science:
- Pharmacology
- Microbiology
- Clinical Pharmacy
Context:
- Aminoglycoside antibiotics are crucial in treating severe bacterial infections.
- Understanding their properties is essential for effective and safe clinical use.
Purpose:
- To provide a comprehensive overview of commonly used aminoglycoside antibiotics.
- To discuss their clinical applications, adverse effects, and pharmacokinetic profiles.
- To highlight the importance of antibiotic combinations and therapeutic drug monitoring.
Summary:
- Details indications, side effects, dosage, and pharmacokinetics for gentamicin, tobramycin, sisomicin, kanamycin, amikacin, and streptomycin.
- Briefly touches upon antibiotic combinations involving aminoglycosides.
- Discusses the significance of evaluating aminoglycoside serum concentrations for therapeutic drug monitoring.
Impact:
- Aids clinicians in selecting appropriate aminoglycosides and optimizing treatment regimens.
- Supports the safe and effective use of these vital antibiotics.
- Emphasizes the role of pharmacokinetic analysis in patient management.