Related Experiment Videos
Pregnancy outcome in carriers of fragile X
J Kallinen1, K Korhonen, S Kortelainen
1Department of Obstetrics and Gynaecology, Kuopio University Hospital, Finland.
Objective:
To evaluate pregnancy outcome in women who are carriers of fragile X.
Design:
Cross-sectional case-control study.
Setting:
Department of Obstetrics and Gynaecology, Kuopio University Hospital, Finland.
Sample:
Sixty-three singleton pregnancies in carriers of fragile X who were referred for genetic counselling and prenatal diagnosis to Kuopio University Hospital.
Methods:
Logistic regression analysis was used to compare pregnancy outcome in women who are fragile X carrier with outcome of the general obstetric population.
Results:
Carriers of fragile X often experienced more bleeding in late pregnancy than did the reference group. Otherwise, the course and outcome of pregnancy were comparable in both groups.
Conclusion:
Pregnancy outcome in women who are carriers of fragile X is favourable. There is no need to initiate special fetal monitoring because of the fragile X status of the woman.