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Related Experiment Videos

Vasodilator system for the face.

G Gonzalez, B M Onofrio, F W Kerr

    Journal of Neurosurgery
    |June 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Researchers discovered a dual vasodilator system in cats controlling facial blood flow. This system originates in the brain stem, complementing the existing sympathetic vasoconstrictor pathways for facial skin.

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    Area of Science:

    • Neuroscience
    • Physiology
    • Vascular Biology

    Background:

    • Previous research indicated radiofrequency coagulation of the trigeminal ganglion caused facial flushing.
    • This suggested a potential vasodilator pathway influencing facial blood vessels.

    Purpose of the Study:

    • To investigate and delineate a vasodilator system controlling blood flow to the face in cats.
    • To understand the neural pathways involved in facial vasodilation.

    Main Methods:

    • Experiments were conducted on cats.
    • Stereotaxic stimulation of facial and trigeminal nuclei in the brain stem was employed.
    • Neural pathways involving the facial and trigeminal nerves were traced.

    Main Results:

    Related Experiment Videos

    • A vasodilator system was identified originating from the brain stem with the facial nerve.
    • This system travels via the greater superficial petrosal nerve to the trigeminal ganglion.
    • Vasodilator fibers also directly exit the brain stem with the trigeminal nerve.
    • Stimulation elicited vasodilator effects, confirming dual vasomotor control.

    Conclusions:

    • Cats possess a dual vasomotor control system for facial cutaneous blood vessels.
    • This includes the classical sympathetic vasoconstrictor system and a newly described vasodilator system.
    • The vasodilator system can produce significant changes in facial vessel caliber, opposing sympathetic effects.