Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Substance P.

D G Snijdelaar1, R Dirksen, R Slappendel

  • 1Department of Anesthesiology/Pain Center, University Hospital, Nijmegen, The Netherlands. dik.snijdelaar@usa.net

European Journal of Pain (London, England)
|August 25, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Barriers to Registration in the National Donor Registry in Nations Using the Opt-In System: A Review of the Literature.

Transplantation proceedings·2018
Same author

Video-Based E-Learning in Communication Skills for Physicians Provides Higher Agreement to Tissue Donation.

Transplantation proceedings·2016
Same author

Reduction of red blood cell transfusions by implementation of a concise pretransfusion checklist.

Transfusion medicine (Oxford, England)·2016
Same author

Patient blood management in Europe.

British journal of anaesthesia·2012
Same author

Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines.

British journal of anaesthesia·2010
Same author

Isoflurane attenuates pulmonary interleukin-1beta and systemic tumor necrosis factor-alpha following mechanical ventilation in healthy mice.

Acta anaesthesiologica Scandinavica·2009

Substance P, a key neuropeptide in pain signaling, has a debated role in nociception. This review explores its function and potential for novel pain treatments.

Area of Science:

  • Neuroscience
  • Pain Research
  • Pharmacology

Background:

  • Substance P is a neuropeptide implicated in pain transmission.
  • Despite decades of research, its precise function in nociception remains debated.
  • Understanding Substance P's role is crucial for pain management.

Purpose of the Study:

  • To review current knowledge on Substance P's function in pain.
  • To highlight the implications of this knowledge for developing new pain therapies.

Main Methods:

  • Literature review of existing research on Substance P and pain.
  • Analysis of studies investigating Substance P's role in nociceptive processes.

Main Results:

  • Substance P is a significant modulator of pain signaling.

Related Experiment Videos

  • Evidence suggests a complex role in both facilitating and modulating pain perception.
  • Its involvement in neurogenic inflammation is well-documented.

    • Conclusions:

    • Substance P remains a critical target for pain research.
    • Further investigation is needed to fully elucidate its mechanisms for therapeutic development.
    • Targeting Substance P pathways offers potential for innovative pain treatments.