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Solid-phase synthesis of a modified 13-residue seminalplasmin fragment on 1,6-hexanediol diacrylate-crosslinked
C Arunan1, R Nagaraj, V N Rajasekharan Pillai
1School of Chemical Sciences, Mahatma Gandhi University, Kottayam, 686560, Kerala, India. mgu@md2.vsnl.net.in
Peptides
|August 26, 2000
Abstract:
A novel 1,6-hexanediol diacrylate cross-linked resin was prepared that was subsequently functionalized by using chloromethyl methyl ether to afford a high-capacity resin. The resin exhibited good swelling and its application in the successful synthesis of a 13-residue peptide corresponding to the fragment of seminalplasmin has been illustrated. The resin was chemically inert at peptide synthetic conditions.