[Percutaneous treatment of multiple heart defects]

Area of Science:

• Pediatric Cardiology
• Interventional Cardiology
• Congenital Heart Disease

Background:

• Multiple congenital heart defects (CHDs) present complex therapeutic challenges.
• Percutaneous interventions are increasingly utilized for various cardiac conditions.

Purpose of the Study:

• To evaluate the feasibility and outcomes of percutaneous interventions in pediatric patients with multiple CHDs.
• To assess the efficacy of these minimally invasive procedures in improving hemodynamic parameters.

Main Methods:

• Retrospective review of 6 pediatric cases with multiple CHDs.
• Procedures included occlusion of patent ductus arteriosus (PDA), balloon angioplasty for coarctation of the aorta (AC), pulmonary valve stenosis (PVS), and aortic stenosis (AE).
• One case of Shone's syndrome involved angioplasty and valvuloplasty.

Main Results:

• Successful occlusion of PDA in all patients using coils or occluders.
• Significant reduction in valvular gradients post-intervention: AC (46 to 9 mmHg), PVS (110 to 10 mmHg), AE (40 to 14 mmHg).
• One patient with Shone's syndrome underwent successful angioplasty and valvuloplasty, with subsequent surgical repair for subaortic stenosis.

Conclusions:

• Percutaneous intervention is a feasible and effective treatment modality for select pediatric patients with multiple CHDs.
• Minimally invasive approaches can lead to significant hemodynamic improvement and positive clinical outcomes.
• These interventions can be safely performed in conjunction with surgical management for complex CHD cases.