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Evaluation of the iScreen digital screening system for amblyogenic factors
1Department of Ophthalmology, University of British Columbia, Vancouver.
Background:
A digital photoscreener, the iScreen screening system, is now available to detect amblyogenic factors. We carried out a prospective study to evaluate the accuracy of the device in detecting anisometropia, significant refractive error, strabismus and opacities of the ocular media.
Methods:
A total of 449 consecutive patients (median age 7 years) from a private pediatric ophthalmology practice underwent screening with the iScreen photoscreener operated by a minimally trained technician. The results were compared to the masked clinical examination of a pediatric ophthalmologist.
Results:
The iScreen device had a sensitivity of 92.4%, specificity of 89.1%, positive predictive value of 94.1% and false-negative rate of 13.8%. Of the 21 patients with a false-negative result, 12 had myopia of less than -1.50 dioptres. High hyperopia was missed in two patients, high astigmatism in one, unequal cylindrical error in one and strabismus in five.
Interpretation:
The iScreen digital photoscreener produced accurate and timely screening for potentially amblyogenic defects in the study population.
