Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

New advances in pharmacogenomics.

B Destenaves1, F Thomas

  • 1GENSET SA, Genomic Research Centre, Department of Pharmacogenomics and Medical Affairs, Evry, France.

Current Opinion in Chemical Biology
|August 26, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Parenteral artesunate compliance and hospital outcomes in children under five with suspected severe malaria in Sierra Leone.

Public health action·2026
Same author

Defining the oxidation site in Cu(II) and Ni(II) complexes of ligands combining amido, phenolato and pyridine donors.

Dalton transactions (Cambridge, England : 2003)·2025
Same author

3D mesh-augmented hiatal hernia repair in patients with GERD: A 3-year single-center experience.

Hernia : the journal of hernias and abdominal wall surgery·2025
Same author

Ecology of vertical tumor transmission in the freshwater cnidarian Hydra oligactis.

Scientific reports·2025
Same author

Marine transmissible cancer navigates urbanized waters, threatening spillover.

Proceedings. Biological sciences·2024
Same author

Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians.

Open biology·2023

Pharmacogenomics will significantly impact new drug development by revealing how gene variations affect drug outcomes. Technical challenges in genetic analysis are being resolved to enhance its application.

Area of Science:

  • Pharmacogenomics
  • Drug Development
  • Genetics

Background:

  • Gene polymorphism is known to influence drug toxicity and efficacy.
  • Pharmacogenomics applications are crucial for personalized medicine.
  • Existing technical limitations hinder widespread pharmacogenomic adoption.

Purpose of the Study:

  • To highlight the future impact of pharmacogenomics on drug development.
  • To discuss the influence of gene polymorphism on drug response.
  • To address the overcoming of technical limitations in pharmacogenomics.

Main Methods:

  • Review of existing publications on pharmacogenomics.
  • Analysis of gene polymorphism's role in drug efficacy and toxicity.
  • Identification of technical advancements in marker generation, genotyping, and biostatistical analysis.

Related Experiment Videos

Main Results:

  • Pharmacogenomics is poised to revolutionize drug development.
  • Gene variations demonstrably impact how individuals respond to medications.
  • Progress is being made in overcoming technical hurdles in genetic analysis.

Conclusions:

  • Pharmacogenomics will play a pivotal role in the future of drug discovery and development.
  • Understanding gene-drug interactions is key to improving therapeutic outcomes.
  • Advancements in technology are paving the way for broader pharmacogenomic implementation.