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[Preparation, evaluation of specificity and use of anti-Le monoclonal antibodies]

M I Lapenkov, T L Nikolaeva, E A Aborina

    Sudebno-Meditsinskaia Ekspertiza
    |August 29, 2000
    PubMed

    Anti-Le(a) and anti-Le(b) monoclonal antibodies were obtained and attempts at evaluating their epitope specificity have been made. A method for identification of Lewis phenotypes in salivary specimens by dot-I enzyme immunoassay has been developed. Analyses of salivary samples from 72 donors detected donors with phenotypes Le(a-b-) and Le(a+b+), which was confirmed by hemagglutination test.

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