Related Experiment Video
Updated: Aug 19, 2026

Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands
Published on: October 2, 2018
Actin in the cytoplasm of adrenocortical cells
Abstract:
Rat or hamster adrenocortical cells contain a network of filaments mostly 40-80 A in diameter, which is particularly evident at the cell periphery. In frozen sections, adrenocortical cells fix (particularly at their periphery) anti-actin autoantibodies present in sera of patients with chronic aggressive hepatitis. It is concluded that the peripheral network of adrenocortical cells contains contractile proteins (at least actin) and the implication of such proteins in steroid secretion is discussed.
Related Concept Videos
Hypothalamic-Pituitary Axis
Introduction to Actin
Actin Polymerization and Cell Motility
Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate.
Anatomy of the Adrenal Glands
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct regions...
Hormones of the Adrenal Glands
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and corticosterone...
Cushing Syndrome II: Pathophysiology

