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Why do we lack an effective vaccine against herpes simplex virus infections?
S P Deshpande1, U Kumaraguru, B T Rouse
1Department of Microbiology, University of Tennessee, Knoxville 37996-0845, USA.
Microbes and Infection
|August 30, 2000
Abstract:
This review discusses the possible causes for the lack of an effective antiherpes vaccine. Future prospects of vaccines based on the current knowledge of immune responses to herpes viruses are discussed. It is argued that vaccines capable of expanding CD8 T-cell memory responses should be the focus of future anti-herpes simplex virus research.