[Cystic adrenal lesion. Incidental finding].

Area of Science:

• Endocrinology
• Pathology
• Radiology

Background:

• Adrenal masses are common incidental findings during abdominal imaging.
• Non-functioning adrenal masses require careful characterization to rule out malignancy.
• Cystic adrenal masses are rare and present diagnostic challenges.

Observation:

• An incidentally discovered non-functioning cystic adrenal mass was identified during an abdominal ultrasound for unrelated symptoms.
• The lesion was classified as a multilocular pseudocyst based on its imaging and pathological features.
• Histological examination revealed wall fibrosis and calcification.

Findings:

• The pseudocyst lining expressed Factor VIII, a marker typically associated with vascular endothelium.
• This finding suggests a potential vascular origin for the adrenal pseudocyst.
• The mass was non-functioning, meaning it did not produce excess hormones.

Implications:

• This case highlights the importance of thorough evaluation of incidentally found adrenal masses.
• The expression of Factor VIII in the pseudocyst lining provides insight into the potential histogenesis of adrenal cysts.
• Further research may elucidate the specific vascular origins of such pseudocysts.