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[Parvovirus B19 infection in hydrops fetalis]
L Kaiser1, F Sükösd, B Veszprémi
1Pécsi Tudományegyetem, Altalános Orvostudományi Kar, Patológiai Intézet.
Orvosi Hetilap
|August 30, 2000
Summary
Non-immune hydrops fetalis is often caused by factors other than Rh incompatibility. Parvovirus B19 infection was a significant cause in this study, suggesting potential outbreaks.
Area of Science:
- Perinatology
- Fetal Pathology
- Infectious Diseases
Context:
- Retrospective analysis of 210 fetal autopsies (1992-1999).
- Identified 15 cases of hydrops fetalis.
- Investigated etiologies beyond Rh incompatibility.
Purpose:
- To determine the causes and pathomechanisms of non-immune hydrops fetalis.
- To assess the role of parvovirus B19 in fetal hydrops.
- To discuss diagnostic and management implications.
Summary:
- Only one case of hydrops fetalis was due to Rh incompatibility.
- Other identified causes included cystic hygroma, twin-to-twin transfusion, sacrococcygeal teratoma, congenital heart disease, X0 monosomy, and parvovirus B19 infection.
- Parvovirus B19 infection was confirmed in 4 cases, a higher incidence than previously reported, with a potential outbreak suggested in 1998.
Impact:
- Highlights the importance of investigating non-immune causes of hydrops fetalis.
- Suggests parvovirus B19 as a significant etiological agent.
- Informs prenatal diagnosis and management strategies for fetal hydrops.