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Immunological hiding of herpesvirus-infected cells
H W Favoreel1, H J Nauwynck, M B Pensaert
1Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Belgium.
Archives of Virology
|August 30, 2000
Abstract:
Over the past years, numerous research groups have discovered various strategies that herpesviruses use to hide themselves from recognition by the immune system of their hosts. The current review gives a summary of this research, with emphasis on the mechanisms by which herpesvirus-infected cells escape from elimination by complement, phagocytes, cytotoxic T-lymphocytes and/or natural killer cells.