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Related Experiment Videos

Asymmetric sweating in a child with multiple sclerosis.

M Ueno1, Y Tokunaga, S Terachi

  • 1Department of Pediatrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

Pediatric Neurology
|August 30, 2000
PubMed
Summary
This summary is machine-generated.

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Multiple sclerosis (MS) can cause excessive sweating due to central nervous system lesions. In a young patient, hypothalamic involvement on MRI correlated with localized hyperhidrosis during an MS relapse.

Area of Science:

  • Neurology
  • Neuroimaging
  • Autonomic Nervous System Function

Background:

  • Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system.
  • Autonomic dysfunction, including sudomotor abnormalities, can occur in MS.
  • Hyperhidrosis, or excessive sweating, can be a challenging symptom in neurological conditions.

Observation:

  • A 10-year-old male with a recent diagnosis of MS presented with unilateral hyperhidrosis affecting the right forehead and shoulder.
  • Neurological examination revealed no deficits in sudomotor function.
  • Symptoms occurred during a relapse, 3 months after MS onset.

Findings:

  • Magnetic resonance imaging (MRI) revealed a T2-weighted hyperintensity in the left hypothalamus.

Related Experiment Videos

  • The lesion's location suggested a potential link between hypothalamic dysfunction and the observed hyperhidrosis.
  • The findings point towards a central nervous system origin for the sweating abnormality.

    • Implications:

    • Hypothalamic lesions may manifest as focal autonomic dysregulation, such as hyperhidrosis, in pediatric MS.
    • This case highlights the importance of considering central autonomic pathways in the evaluation of sweating abnormalities in MS patients.
    • Neuroimaging findings can help elucidate the pathophysiology of complex MS-related symptoms.