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Updated: Aug 14, 2026

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
Published on: May 12, 2019
Colonic carcinoma after ureterosigmoidostomy
1Department of Colorectal Surgery, Wycombe Hospital, Queen Alexandra Road, High Wycombe, Buckinghamshire HP11 2TT, UK. andyhuang@talk21.com
Abstract:
Urinary carcinogens promote late malignant transformation of the colon after a ureterosigmoidostomy. An unusual case is presented where, despite the early removal of the latter and hence cessation of urine flow, a colonic carcinoma developed at the site of previous anastomosis. The importance of surveillance of all patients who have undergone this procedure to avoid an iatrogenic cancer is emphasised.
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