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Updated: Jul 20, 2026

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
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Enantiospecific synthesis of N-Boc-Adda: a linear approach

C Pearson1, K L Rinehart, M Sugano

  • 1Roger Adams Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

Organic Letters
|August 31, 2000
PubMed
Summary

Researchers synthesized the complex amino acid Adda, a component of cyanobacterial toxins, in 13 steps. A novel one-pot method efficiently converted an intermediate to the final product, also applicable to beta-amino acid synthesis.

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