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Related Experiment Videos

Lymphoma in the ear.

P Merkus1, M P Copper, M H Van Oers

  • 1Department of Otolaryngology and Head and Neck Surgery, Academical Medical Center, Amsterdam, The Netherlands. P.Merkus@amc.uva.nl

ORL; Journal for Oto-Rhino-Laryngology and Its Related Specialties
|August 31, 2000
PubMed
Summary
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Malignant ear lymphomas are rare, with only 16 cases reported. Early diagnosis via CT scans is crucial for therapy-resistant otitis or facial paralysis to rule out malignancy.

Area of Science:

  • Oncology
  • Otorhinolaryngology

Background:

  • Malignant tumors of the ear are uncommon, with squamous cell carcinomas and adenocarcinomas being the most frequent.
  • Lymphoma of the ear is a rare clinical entity.

Observation:

  • This report details two cases of primary ear lymphoma: an anaplastic large cell lymphoma in the external auditory meatus and a B-cell non-Hodgkin's lymphoma in the mastoid process.
  • A comprehensive literature review identified only 16 previously reported cases of ear lymphomas since 1947.

Findings:

  • The presented cases highlight the diverse presentations of ear lymphomas.
  • The literature review underscores the rarity of this condition, with a limited number of documented instances.

Implications:

  • In cases of persistent otitis or peripheral facial paralysis unresponsive to treatment, malignancy, including lymphoma, should be suspected and investigated using computed tomography (CT) of the mastoid.

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  • Prompt histopathological diagnosis using unfixed specimens is recommended.
  • Standardized treatment protocols for ear lymphomas have not yet been established, necessitating further research and clinical consensus.