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Published on: November 4, 2010
Air quality and pediatric emergency room visits for asthma in Atlanta, Georgia, USA
P E Tolbert1, J A Mulholland, D L MacIntosh
1Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Insights
Childhood asthma exacerbations are linked to air pollution. Higher levels of ozone and particulate matter (PM10) significantly increased pediatric emergency room visits for asthma during summer months in Atlanta.
Area of Science:
- Environmental Health
- Pediatric Pulmonology
- Epidemiology
Background:
- Pediatric asthma is a significant public health concern.
- Environmental factors, particularly air quality, are suspected triggers for asthma exacerbations.
Purpose of the Study:
- To investigate the spatio-temporal relationship between air quality indices and pediatric emergency room visits for asthma.
- To quantify the association between specific air pollutants and asthma exacerbations in children.
Main Methods:
- A spatio-temporal analysis of approximately 130,000 emergency visits (6,000 for asthma) in Atlanta, GA (1993-1995).
- Logistic regression and Bayesian models were used, linking patient residential zip codes to spatially resolved ozone and particulate matter (PM10) levels.
- Covariates included temporal and demographic factors.
Main Results:
- A 20 ppb increase in maximum 8-hour ozone was associated with a relative risk of 1.04 (p < 0.05) for asthma visits.
- A 15 µg/m³ increase in PM10 was associated with a relative risk of 1.04 (p < 0.05).
- Significant exposure-response trends were observed for both ozone and PM10.
Conclusions:
- This study provides evidence supporting the link between ambient air pollution and childhood asthma exacerbations.
- Ozone and PM10 are significant contributors to pediatric asthma emergency room visits.
- Public health strategies should consider air quality interventions to mitigate childhood asthma.
Abstract:
Pediatric emergency room visits for asthma were studied in relation to air quality indices in a spatio-temporal investigation of approximately 130,000 visits (approximately 6,000 for asthma) to the major emergency care centers in Atlanta, Georgia, during the summers of 1993-1995. Generalized estimating equations, logistic regression, and Bayesian models were fitted to the data. In logistic regression models comparing estimated exposures of asthma cases with those of the nonasthma patients, controlling for temporal and demographic covariates and using residential zip code to link patients to spatially resolved ozone levels, the estimated relative risk per 20 parts per billion (ppb) increase in the maximum 8-hour ozone level was 1.04 (p < 0.05). The estimated relative risk for particulate matter less than or equal to 10 microm in aerodynamic diameter (PM10) was 1.04 per 15 microg/m3 (p < 0.05). Exposure-response trends (p < 0.01) were observed for ozone (>100 ppb vs. <50 ppb: odds ratio = 1.23, p = 0.003) and PM10 (>60 microg/m3 vs. <20 microg/m3: odds ratio = 1.26, p = 0.004). In models with ozone and PM10, both terms became nonsignificant because of collinearity of the variables (r= 0.75). The other analytical approaches yielded consistent findings. This study supports accumulating evidence regarding the relation of air pollution to childhood asthma exacerbation.
Related Concept Videos
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma I: Introduction
Asthma III: Clinical Manifestations

