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Appendiceal perforation in children diagnosed in a pediatric emergency department
D S Nelson1, B Bateman, R G Bolte
1Primary Children's Medical Center, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City 84113, USA. doug.nelson@hsc.utah.edu
Insights
Appendiceal perforation (AP) affects nearly half of pediatric acute appendicitis (AA) cases. Younger children with symptoms like vomiting and fever are at higher risk for AP, necessitating earlier diagnosis and treatment.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Emergency Medicine
Background:
- Acute appendicitis (AA) is a common surgical emergency in children.
- Appendiceal perforation (AP) is a significant complication of AA, leading to increased morbidity.
- Understanding factors associated with AP is crucial for timely intervention.
Purpose of the Study:
- To determine the incidence of appendiceal perforation (AP) in children diagnosed with acute appendicitis (AA).
- To identify clinical and demographic factors associated with AP in pediatric patients.
Main Methods:
- Retrospective chart review of 131 children under 17 years old diagnosed with AA.
- Data collected from the Emergency Department (ED) of Primary Children's Medical Center (PCMC).
- Analysis of patient demographics, symptom duration, physical findings, and laboratory results.
Main Results:
- The overall incidence of AP was 47%.
- Patients with AP were younger (median age 8.0 vs 11.0 years) and had longer illness duration (3.0 vs 1.4 days).
- Vomiting, fever, higher temperatures, and elevated leukocyte band forms were associated with AP.
Conclusions:
- Younger age, prolonged illness, vomiting, and fever are risk factors for AP in children with AA.
- Unexpectedly, higher total white blood cell counts and delayed diagnosis did not correlate with AP.
- Increased physician awareness and prompt referral are recommended to reduce AP rates.
Objective:
To determine the incidence of appendiceal perforation (AP) among children with acute appendicitis (AA) and determine factors associated with AP.
Design:
Retrospective chart review.
Setting:
Emergency department (ED) of Primary Children's Medical Center (PCMC).
Patients:
131 children less than 17 years of age with AA diagnosed in the PCMC ED.
Results:
The overall rate of AP was 47%. One hundred eleven (85%) children with AA were correctly diagnosed on their first ED visit. Patients with AP had a significantly (P < 0.05) lower median age (8.0 vs 11.0 years), longer duration of illness (3.0 vs 1.4 days), greater incidence of vomiting and fever by history (91% vs 69% and 83% vs 58%, respectively), higher median temperatures (39.0 degrees vs 38.3 degrees C), and higher proportions of leukocyte (WBC) band forms (14% vs 5%). Patients with AP did not differ from those without AP with respect to total WBC count, hour of arrival, or number of ED visits.
Conclusions:
The rate of AP among pediatric patients with AA is greater among younger children and is associated with vomiting, prolonged illness, and higher body temperatures. Unexpectedly, patients with AP did not have higher total WBC values, more frequent late night arrivals, a longer time interval prior to surgery, or more ED visits prior to diagnosis. These findings suggest that efforts to decrease the rate of AP should be directed toward heightening awareness among primary care physicians regarding the high rate of AP in children, with an emphasis on early ED and surgical referral.
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