Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Structure and function of cytochrome bc complexes.

E A Berry1, M Guergova-Kuras, L S Huang

  • 1Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA. EABerry@LBL.gov

Annual Review of Biochemistry
|August 31, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Clinical characteristics of pediatric <i>Mycoplasma pneumoniae</i> necrotizing pneumonia with co-infections].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2026
Same author

[A case of infective endocarditis caused by <i>Neisseria</i> mucosa in a child].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2024
Same author

Comparison of a novel form of zinc with zinc oxide bolus licensed for prevention of facial eczema, and interaction with copper oxide in sheep.

Australian veterinary journal·2022
Same author

[A multicenter epidemiological study of acute bacterial meningitis in children].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2022
Same author

[Empirical antibiotic strategies for acute respiratory infections in children].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2022
Same author

[Research progress on gasdermin D mediated pyroptosis and cardiovascular diseases].

Zhonghua xin xue guan bing za zhi·2022
Same journal

Lactate as a Chemical Modification on Proteins and Metabolites.

Annual review of biochemistry·2026
Same journal

Nucleocytoplasmic Transport.

Annual review of biochemistry·2026
Same journal

Packaging of Single-Stranded RNA in Viruses and Virus-Like Particles.

Annual review of biochemistry·2026
Same journal

Shaping of the Infant Gut Microbiome by Milk Oligosaccharides.

Annual review of biochemistry·2026
Same journal

Proteostasis Deregulation by Metabolism Drives the Hallmarks of Cancer.

Annual review of biochemistry·2026
Same journal

JoAnne Stubbe's Radical Path: A Story of Passion, Curiosity, and Persistence.

Annual review of biochemistry·2026
See all related articles

Cytochrome bc complexes are diverse electron-transferring proteins crucial for energy conservation. Recent advances in X-ray structures and mutagenesis illuminate their mechanisms in cellular respiration and photosynthesis.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Bioenergetics

Background:

  • Cytochrome bc complexes are vital membrane protein complexes involved in electron transfer and proton translocation.
  • They are found across diverse organisms, including mitochondria, bacteria, chloroplasts, and cyanobacteria.
  • These complexes conserve energy by creating an electrochemical proton gradient.

Purpose of the Study:

  • To summarize recent advancements in understanding cytochrome bc complexes.
  • To highlight the role of site-directed mutagenesis in defining conserved residue functions.
  • To discuss the impact of emerging X-ray structures on the field.

Main Methods:

  • Application of site-directed mutagenesis to investigate protein function.
  • X-ray crystallography to determine high-resolution structures of complexes.

Related Experiment Videos

  • Comparative analysis of diverse cytochrome bc complexes.

    • Main Results:

    • Detailed functional roles of conserved residues have been elucidated.
    • X-ray structures of several mitochondrial bc1 complexes are now available.
    • Key domains of the chloroplast/cyanobacterial b6f complex have been structurally characterized.

    Conclusions:

    • Structural and functional insights into cytochrome bc complexes have significantly advanced.
    • These studies provide a foundation for understanding energy transduction in biological systems.
    • Further research promises deeper understanding of these essential bioenergetic machines.