Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Visual prognostic value of the pattern electroretinogram in chiasmal compression.

D N Parmar1, A Sofat, R Bowman

  • 1Department of Neurosciences, King's College Hospital, London SE5 9RS, UK.

The British Journal of Ophthalmology
|September 1, 2000
PubMed
Summary

The pattern electroretinogram (PERG) N95:P50 ratio can predict visual field changes after surgery for pituitary tumors compressing the optic chiasm. A normal ratio indicates a better prognosis for visual function recovery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pattern ERGs suggest a possible retinal contribution to the visual acuity loss in acute optic neuritis.

Documenta ophthalmologica. Advances in ophthalmology·2022
Same author

Visual outcomes and predictors in optic pathway glioma: a single centre study.

Eye (London, England)·2022
Same author

Cemented Exeter total hip arthroplasty with a 32 mm head on highly crosslinked polyethylene: Does age influence functional outcome, satisfaction, activity, stem migration, and periprosthetic bone mineral density?

Bone & joint research·2019
Same author

Artificial scotoma estimation based on population receptive field mapping.

NeuroImage·2017
Same author

Unmet needs of cataract blind children in special schools in Southeast Nigeria.

Eye (London, England)·2017
Same author

The pattern of retinal ganglion cell dysfunction in Leber hereditary optic neuropathy.

Mitochondrion·2017

Area of Science:

  • Ophthalmology
  • Neuroscience

Background:

  • Pituitary tumors can cause optic chiasm compression, leading to visual loss.
  • Retinal ganglion cell degeneration may influence the permanence of visual deficits.
  • Pattern electroretinogram (PERG) N95 component may reflect retinal ganglion cell function.

Purpose of the Study:

  • To evaluate the prognostic value of the PERG N95:P50 ratio for visual function after surgery for chiasmal compression.
  • To determine if PERG can predict visual field outcomes following decompressive surgery.

Main Methods:

  • Retrospective analysis of electrodiagnostic records from 36 patients (72 eyes) with chiasmal compression.
  • Assessment of the relationship between preoperative PERG N95:P50 ratio and postoperative visual field changes.

Related Experiment Videos

Main Results:

  • A significant association was found between the PERG N95:P50 ratio and postoperative visual field improvement (p=0.01).
  • Eyes with a normal N95:P50 ratio showed a higher rate of visual field improvement (65%) compared to those with an abnormal ratio (27%).
  • No significant relationship was observed between the PERG N95:P50 ratio and visual acuity outcomes.

Conclusions:

  • The PERG N95:P50 ratio serves as a valuable preoperative prognostic indicator for visual function in patients with chiasmal compression.
  • PERG assessment can aid in predicting visual field recovery after surgical decompression.