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Respiratory fungal allergy.
V P Kurup1, H D Shen, B Banerjee
1Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Wisconsin, Milwaukee, USA.
Microbes and Infection
|September 1, 2000
Summary
Fungal allergy, including asthma and rhinitis, stems from spore exposure. Future control may involve epitope-specific immunotherapy and vaccination against common allergens.
Area of Science:
- Mycology
- Immunology
- Allergology
Background:
- Fungal spores are common environmental triggers for allergic diseases.
- Allergic conditions include allergic rhinitis, conjunctivitis, bronchial asthma, and allergic bronchopulmonary mycoses.
- Understanding the role of fungi in allergy is crucial for public health.
Purpose of the Study:
- To review common allergenic fungi and their allergens.
- To discuss the immunopathogenesis of fungal allergy.
- To explore future diagnostic and therapeutic strategies for fungal allergy.
Main Methods:
- Literature review of common allergenic fungi.
- Analysis of immunopathogenic mechanisms.
- Evaluation of current diagnostic assays.
- Assessment of future control strategies like immunotherapy and vaccination.
Main Results:
- Identification of prevalent allergenic fungi and specific allergens.
- Elucidation of the immune responses involved in fungal allergy.
- Overview of diagnostic methods for fungal allergy.
- Discussion on the potential of epitope-specific immunotherapy and vaccination.
Conclusions:
- Fungal allergy is a significant health concern resulting from spore exposure.
- Effective diagnosis and management are essential.
- Future research should focus on advanced immunotherapies and vaccines for better control.