Related Experiment Videos
Acute myocardial injury: an entity of acute coronary syndromes
1Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur.
The Medical Journal of Malaysia
|June 1, 1997
Insights
This case study highlights a 46-year-old man with unstable angina and chest pain at rest. Elevated troponin T levels indicated significant acute myocardial injury, despite undetectable CKMB.
Area of Science:
- Cardiology
- Internal Medicine
- Emergency Medicine
Background:
- Unstable angina (Braunwald's class IIIB1) presents with chest pain at rest.
- Inferolateral ischemia on electrocardiogram (ECG) is a critical finding.
- Biomarker assessment is crucial for diagnosing acute myocardial injury.
Observation:
- A 46-year-old Indian man presented with symptoms of unstable angina.
- Electrocardiogram revealed inferolateral ischemia during chest pain at rest.
- Serial total creatine kinase (CK) levels were elevated.
Findings:
- Creatine kinase-MB (CKMB) was not detected in serial measurements.
- Serial serum troponin T levels were significantly elevated.
- The findings suggest significant acute myocardial injury.
Implications:
- Troponin T elevation is a sensitive marker for myocardial damage, even with normal CKMB.
- Early recognition and management of unstable angina are vital.
- This case underscores the importance of comprehensive cardiac biomarker evaluation.
Abstract:
A 46-year-old Indian man was admitted with unstable angina (Braunwald's class IIIB1)--the chest pain at rest was associated with inferolateral ischaemia on the ECG at admission. His serial total creatine kinase levels were elevated but CKMB was not detected. Serial serum troponin T levels were significantly raised suggesting the presence of significant acute myocardial injury.