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Bacterial infection of central venous catheters in short-term total parenteral nutrition

L Chan1, Y F Ngeow, N Parasakthi

  • 1Department of Anaesthesiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

The Medical Journal of Malaysia
|September 1, 2000
PubMed

Insights

Catheter-related infection is common in critically ill patients receiving parenteral nutrition. Strict protocols and specialized teams can help control central venous catheter infections.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Microbiology

Background:

  • Central venous catheters are essential for parenteral nutrition in intensive care units.
  • Catheter-related infections pose a significant risk to patient safety and outcomes.

Purpose of the Study:

  • To investigate the incidence and sources of catheter-related infections in severely ill, ventilated patients.
  • To determine the rate of catheter-related bacteremia (CRB) and identify causative microorganisms.

Main Methods:

  • Microbiological analysis of catheter segments (exit site, hub, subcutaneous, tip) using Maki's SQ technique.
  • Qualitative cultures of parenteral nutrition and blood samples.
  • Analysis of 29 removed central venous catheters from 14 patients.

Main Results:

  • 90% of removed catheters (26/29) showed positive cultures.
  • A catheter-related bacteremia (CRB) rate of 24% (7/29) was observed.
  • Patient skin flora was the primary source of infection; coagulase-negative staphylococci, Acinetobacter, and Klebsiella were common pathogens.

Conclusions:

  • High rates of catheter colonization and CRB necessitate stringent infection control measures.
  • Specialized intravenous therapy teams and strict protocols for catheter insertion and maintenance are crucial.
  • Focusing on prevention strategies can reduce infective complications associated with central venous catheters.

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