Cutaneous malignant melanoma in children
Related Experiment Video
Updated: Oct 13, 2026

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
Published on: June 7, 2019
E Vandeweyer1, F Sales, R Deraemaecker
1Department of Plastic and Reconstructive Surgery, Institut Jules Bordet, Bruxelles, Belgium.
Unlabelled:
Although rare, malignant melanoma does occur in children. As in adults, prognosis clearly depends on rapid diagnosis and early treatment. This paper describes eight cases of confirmed malignant melanoma in children, with full case history and pathological findings. Mean follow-up was 109.8 months. Early diagnosis and low Breslow indices provide good results in the form of absence of recurrence and long-term survival prognosis. The paper also includes a discussion of specific risk factors affecting children. In order to encourage earlier diagnosis and improved prognosis, it must be kept in mind that in children too, the skin as an organ should be included in any physical examination.
Conclusion:
As for adult patients, early clinical detection, speedy histological confirmation and prompt surgery is the only way to achieve a long survival period for children suffering from malignant melanoma.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Pigmentation
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

