Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Smoking--a renal risk factor.

S R Orth1

  • 1Department of Internal Medicine, Ruperto Carola University, Heidelberg, Germany.

Nephron
|September 6, 2000
PubMed
Summary
This summary is machine-generated.

Cigarette smoking significantly increases the risk of kidney disease progression and end-stage renal failure in patients with diabetes and other primary renal diseases. This highlights smoking as a critical, yet often overlooked, risk factor in nephrology.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sympathetic blockade prevents the decrease in cardiac VEGF expression and capillary supply in experimental renal failure.

American journal of physiology. Renal physiology·2010
Same author

[Complementation of eGFR by urinary albumin excretion - the way to a new classification system of chronic kidney disease].

Deutsche medizinische Wochenschrift (1946)·2010
Same author

Cigarette smoking: an important renal risk factor - far beyond carcinogenesis.

Tobacco induced diseases·2009
Same author

[Adverse renal effects of legal and illicit drugs].

Therapeutische Umschau. Revue therapeutique·2002
Same author

Glomerulosclerosis and progression: effect of subantihypertensive doses of alpha and beta blockers.

Kidney international·2001
Same author

Specific organ protection by blocking the renin-angiotensin system.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2001
Same journal

The Impact of High-Altitude Acclimatization on Frontal Lobe Executive Function: The Mediating Effect of Creatinine.

Nephron·2026
Same journal

Expert Commentary of the Recent International Pediatric Nephrology Association IgA Vasculitis Nephritis Guidelines.

Nephron·2026
Same journal

Acute effects of exercise on the nephron index under different conditions in middle-aged males - a preliminary study.

Nephron·2026
Same journal

Lysozyme-Associated Nephropathy in Myeloid Neoplasms: A Clinicopathological and Mass Spectrometric Study of Two Cases.

Nephron·2026
Same journal

Prevalence of COVID-19 Pneumonia and Clinical Characteristics in Hemodialysis Patients During the SARS-CoV-2 Omicron Pandemic.

Nephron·2026
Same journal

Real-World Outcomes of Patients with Monoclonal Gammopathy of Renal Significance.

Nephron·2026
See all related articles

Area of Science:

  • Nephrology
  • Clinical research
  • Epidemiology

Background:

  • Identifying renal failure progression risk factors is crucial in nephrology.
  • Cigarette smoking is an under-recognized but significant risk factor for kidney disease.
  • Diabetologists have long known smoking's adverse effects on kidney health in diabetes.

Observation:

  • Smoking increases the risk of nephropathy in both type 1 and type 2 diabetes.
  • Smoking nearly doubles the progression rate to end-stage renal failure in diabetic patients.
  • A European case-control study identified smoking as an independent risk factor for end-stage renal failure in primary renal diseases like IgA glomerulonephritis and polycystic kidney disease.

Findings:

  • Smoking is an independent risk factor for end-stage renal failure in patients with inflammatory and non-inflammatory renal diseases.

Related Experiment Videos

  • The exact mechanisms of smoking-induced renal damage are not fully understood.
  • Increased blood pressure during smoking is a likely contributor to renal damage, with other mechanisms potentially involved.

    • Implications:

    • The findings underscore the importance of addressing smoking cessation in nephrology and diabetology patient management.
    • Further research is needed to elucidate the precise mechanisms of smoking-mediated renal injury.
    • Clinicians should consider smoking status as a key factor when assessing renal disease progression risk.