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Pharmacogenetics of the alcohol dehydrogenase system
H Jörnvall1, J O Höög, B Persson
1Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Pharmacology
|September 6, 2000
Abstract:
Alcohol dehydrogenase (ADH) constitutes a complex enzyme system with different forms and extensive multiplicity. A combination of constant and variable properties regarding function, multiplicity and structure of ADH is highlighted for the human system and extended to ADH forms in general. Future perspectives suggest continued studies in specific directions for distinction of metabolic, regulatory and pharmacogenetic roles of ADH.