Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ossiculoplasty using hydroxyapatite prostheses: long-term results.

T Shinohara1, K Gyo, T Saiki

  • 1Department of Otolaryngology, Ehime University School of Medicine, Ehime, Japan. shino@m.ehime-u.ac.jp

Clinical Otolaryngology and Allied Sciences
|September 6, 2000
PubMed
Summary

Hydroxyapatite prostheses show moderate success in ossicular chain reconstruction, with hearing improvements in 59% at one year, but rates decline over time. High extrusion rates (16%) were observed, particularly when the prosthesis contacted the tympanic membrane.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Formation and evolution of carbonaceous asteroid Ryugu: Direct evidence from returned samples.

Science (New York, N.Y.)·2022
Same author

Pebbles and sand on asteroid (162173) Ryugu: In situ observation and particles returned to Earth.

Science (New York, N.Y.)·2022
Same author

Sample collection from asteroid (162173) Ryugu by Hayabusa2: Implications for surface evolution.

Science (New York, N.Y.)·2020
Same author

An artificial impact on the asteroid (162173) Ryugu formed a crater in the gravity-dominated regime.

Science (New York, N.Y.)·2020
Same author

Images from the surface of asteroid Ryugu show rocks similar to carbonaceous chondrite meteorites.

Science (New York, N.Y.)·2019
Same author

The geomorphology, color, and thermal properties of Ryugu: Implications for parent-body processes.

Science (New York, N.Y.)·2019

Area of Science:

  • Otolaryngology
  • Biomaterials Science
  • Surgical Innovation

Background:

  • Ossicular chain reconstruction is crucial for restoring hearing in conductive hearing loss.
  • Hydroxyapatite has been explored as a biocompatible material for prostheses.
  • Long-term outcomes of hydroxyapatite ossicular prostheses require further evaluation.

Purpose of the Study:

  • To evaluate the long-term surgical results of ossicular chain reconstruction using hydroxyapatite prostheses.
  • To assess hearing outcomes and prosthesis extrusion rates over a minimum of five years.
  • To compare the efficacy of different hydroxyapatite prosthesis types (P-type vs. T-type).

Main Methods:

  • A retrospective study of 106 ears from 101 patients undergoing ossicular chain reconstruction with hydroxyapatite prostheses.

Related Experiment Videos

  • Follow-up exceeding five years.
  • Success defined by postoperative air-bone gap ≤ 20 dB, air conduction < 40 dB, or hearing gain > 15 dB.

    • Main Results:

    • Initial hearing success was 59% at one year, with higher rates for P-type (68%) than T-type (46%) prostheses.
    • Overall success declined to 50% by year five, with P-type at 60% and T-type at 34%.
    • Prosthesis extrusion occurred in 16% of cases, averaging 27.7 months post-surgery, with increased risk when in contact with the tympanic membrane.

    Conclusions:

    • Hydroxyapatite is a viable material for ossicular prostheses, offering initial hearing improvement.
    • Long-term hearing success rates decrease over time, indicating potential material degradation or displacement.
    • The high extrusion rate, especially with tympanic membrane contact, necessitates technique refinement to improve durability and patient outcomes.