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Related Experiment Videos

Cutaneous primary paracoccidioidomycosis.

M García Bustínduy1, F J Guimerá, P Arévalo

  • 1Department of Dermatology, Hospital Universitario de Canarias, Universidad de La Laguna, Tenerife, Spain. mgarciab@ull.es

Journal of the European Academy of Dermatology and Venereology : JEADV
|September 6, 2000
PubMed
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Paracoccidioidomycosis, a fungal infection, can present years after exposure. This case highlights cutaneous paracoccidioidomycosis in a non-endemic area, suggesting direct skin infection as a possible route.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Dermatology

Background:

  • Paracoccidioidomycosis is endemic to Latin America.
  • Diagnosis in non-endemic regions is challenging due to potential long latency periods (up to 60 years).
  • The respiratory tract is the conventionally accepted primary entry route.

Observation:

  • A 59-year-old man, with 25 years of work history in Venezuela, presented with cutaneous paracoccidioidomycosis.
  • The diagnosis was made in Spain, one year after his return.
  • The patient exhibited no systemic signs or symptoms, and his cell-mediated immunity was not compromised.

Findings:

  • The case presented as isolated cutaneous paracoccidioidomycosis.
  • No evidence of internal organ involvement was detected.

Related Experiment Videos

  • Normal immune function was observed.

    • Implications:

    • This case suggests direct cutaneous inoculation as a potential route of infection for paracoccidioidomycosis.
    • It underscores the importance of considering paracoccidioidomycosis in patients with relevant travel history, even with atypical presentations.
    • Further investigation into alternative infection pathways beyond the respiratory tract may be warranted.