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Post-streptococcal uveitis
E Besada1, S Schatz, S S Saremi
1Nova Southeastern University, College of Optometry, Ft. Lauderdale, Florida, USA.
Optometry (St. Louis, Mo.)
|September 7, 2000
Summary
Bilateral uveitis may indicate a post-streptococcal syndrome. Testing for antistreptolysin O (ASO) antibodies is recommended for patients with uveitis and signs of a prior streptococcal infection.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Rheumatology
Background:
- Group A streptococcal infections can lead to various post-infectious syndromes.
- Bilateral nongranulomatous uveitis is an ocular manifestation that warrants investigation into potential underlying causes.
- Post-streptococcal syndrome has been anecdotally linked to ocular inflammation.
Observation:
- A series of case reports investigated patients presenting with bilateral nongranulomatous anterior uveitis.
- Patients reported a recent history of sore throat, a common symptom of streptococcal infection.
- Physical examination and laboratory blood analysis, including antistreptolysin O (ASO) antibody titer, were performed.
Findings:
- Serological testing revealed elevated ASO antibody titers in affected individuals.
- The uveitis was attributed to a preceding streptococcal infection.
- Treatment with topical corticosteroids resolved the uveitis, and systemic antibiotics addressed potential sequelae of the post-streptococcal syndrome.
Implications:
- Uveitis should be considered a potential clinical manifestation of post-streptococcal syndrome.
- ASO antibody quantification is a valuable diagnostic tool for identifying streptococcal-associated uveitis.
- This finding aids in diagnosing previously idiopathic cases of bilateral nongranulomatous anterior uveitis.