[A case of mania following olanzapine administration]

A 31-year old man, suffering from schizophrenia for 5 years was admitted to the psychiatric ward because of another exacerbation of schizophrenia. Olanzapine treatment was started, in dose 10 mg a day. During treatment mania was observed. First symptoms of hypomania appeared on the 5th day of treatment. Manic symptoms increased, the greatest escalation of mania was observed on the 13th day. Olanzapine dose was reduced to 5 mg a day, and haloperidol was added. Mania retreated. Finally the patient has been treated by haloperidol decanoate 100 mg every two weeks and olanzapine 5 mg a day. The illness has entered a period of remission.