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Obstetric complications and affective psychoses. Two case-control studies based on structured obstetric records
M Bain1, E Juszczak, K McInneny
1Information and Statistics Division, National Health Service in Scotland, Edinburgh.
This study found no increased risk of obstetric complications in individuals with early-onset affective psychoses compared to controls. Findings suggest obstetric history is unlikely to be a significant factor in these conditions.
Area of Science:
- Psychiatry
- Obstetrics
- Epidemiology
Background:
- Limited research exists on obstetric complications in affective psychoses, unlike schizophrenia.
- Affective psychoses encompass conditions like bipolar disorder and major depression.
Purpose of the Study:
- To investigate if obstetric complications are more frequent in individuals with affective psychoses compared to matched controls.
- To assess the relationship between obstetric events and early-onset affective disorders.
Main Methods:
- A case-control study comparing 217 and 84 affective psychosis probands with matched controls.
- Utilized standardized obstetric data recorded shortly after birth for individuals born in Scotland between 1971-1978.
Main Results:
- Abnormal fetal presentation was more common in the 1971-74 affective psychosis cohort.
- Artificial rupture of membranes was more frequent in the 1975-78 affective psychosis cohort.
- These findings were considered likely due to chance.
Conclusions:
- The incidence of obstetric complications is unlikely to be elevated in early-onset affective psychoses.
- Obstetric history does not appear to be a significant risk factor for developing affective psychoses.
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