Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 21, 2026

Cochlear Implantation in the Guinea Pig
09:56

Cochlear Implantation in the Guinea Pig

Published on: June 15, 2018

Histopathological findings in cochlear implants in cats.

G M Clark, H G Kranz, H Minas

    The Journal of Laryngology and Otology
    |May 1, 1975
    PubMed
    Summary

    Cochlear electrode implantation in cats is feasible via the round window or drilled openings without damaging auditory nerve cells. However, drilled openings increase infection risk, potentially causing cochlear damage and cell loss.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A phase I and pharmacokinetic trial of terephthalamidine (NSC 57155) as a 120-hour continuous infusion.

    Investigational new drugs·1998
    Same author

    Chronic study on the neuronal excitability of the cochlear nuclei of the cat following electrical stimulation.

    Acta oto-laryngologica·1998
    Same author

    Studies of prosody perception by cochlear implant patients.

    Audiology : official organ of the International Society of Audiology·1998
    Same author

    Enzyme-linked immunoabsorbent assay-detected p53 protein accumulation: a prognostic factor in a large breast cancer cohort.

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology·1998
    Same author

    Modulation detection interference in cochlear implant subjects.

    The Journal of the Acoustical Society of America·1998
    Same author

    Intracellular responses of the rat anteroventral cochlear nucleus to intracochlear electrical stimulation.

    Brain research bulletin·1998

    Area of Science:

    • Veterinary Medicine
    • Neuroscience
    • Otolaryngology

    Background:

    • Cochlear implants are crucial for auditory restoration.
    • Histopathological studies are essential for evaluating surgical techniques and their impact on delicate inner ear structures.

    Purpose of the Study:

    • To histopathologically assess the safety of cochlear electrode implantation in cats.
    • To compare the outcomes of implantation via the round window versus a drilled opening.

    Main Methods:

    • Histopathological examination of feline cochleae post-electrode implantation.
    • Surgical procedures involving implantation through the round window and drilled openings.

    Main Results:

    • Electrode implantation through the round window or drilled openings did not result in spiral ganglion cell or auditory nerve fiber loss.

    More Related Videos

    Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice
    09:06

    Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

    Published on: January 9, 2019

    Testing a Cochlear Implant Electrode Insertion Training System for Optimal Electrode Array Placement in Different Inner Ear Anatomies
    07:34

    Testing a Cochlear Implant Electrode Insertion Training System for Optimal Electrode Array Placement in Different Inner Ear Anatomies

    Published on: February 6, 2026

    Related Experiment Videos

    Last Updated: Jul 21, 2026

    Cochlear Implantation in the Guinea Pig
    09:56

    Cochlear Implantation in the Guinea Pig

    Published on: June 15, 2018

    Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice
    09:06

    Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

    Published on: January 9, 2019

    Testing a Cochlear Implant Electrode Insertion Training System for Optimal Electrode Array Placement in Different Inner Ear Anatomies
    07:34

    Testing a Cochlear Implant Electrode Insertion Training System for Optimal Electrode Array Placement in Different Inner Ear Anatomies

    Published on: February 6, 2026

  • Drilled openings were associated with a higher incidence of infection and subsequent labyrinthitis.
  • Infection led to significant cochlear structure destruction and spiral ganglion cell loss.

    • Conclusions:

    • Cochlear electrode implantation is achievable in cats with preservation of neural elements.
    • The round window approach appears safer, minimizing the risk of infection and subsequent cochlear damage compared to drilled openings.