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[Effect of dissolved oxygen on mutanolysin fermentation].

T J Liu1, W L Xu, W B Sun

  • 1State Key Laboratory of Microbial Technology, Shandong University, Jinan.

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|September 8, 2000
PubMed
Summary

Dissolved oxygen (DO) significantly impacts mutanolysin fermentation by Streptomyces globisporus S186. Maintaining a suboptimum dissolved oxygen level is crucial for maximizing mutanolysin yield, as both excessive and insufficient oxygen hinder production.

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Area of Science:

  • Microbiology
  • Biochemical Engineering
  • Fermentation Technology

Context:

  • Mutanolysin is an enzyme with potential applications, and its efficient production is of interest.
  • Streptomyces globisporus S186 is the producing microorganism.
  • Optimizing fermentation conditions is key to maximizing enzyme yield.

Purpose:

  • To investigate the effects of dissolved oxygen (DO) levels on mutanolysin fermentation.
  • To determine the optimal DO concentration for mutanolysin production.
  • To identify key parameters influencing DO in the fermentor.

Summary:

  • Dissolved oxygen (DO) is a critical limiting factor in mutanolysin fermentation.
  • Both excessively high and low DO levels negatively affect mutanolysin production by Streptomyces globisporus S186.

Related Experiment Videos

  • Optimal mutanolysin yield is achieved by maintaining a suboptimum DO level, with specific agitation and aeration rates recommended for fermentor cultures.

    • Impact:

    • Provides insights into controlling dissolved oxygen for enhanced enzyme production.
    • Establishes optimal fermentation parameters for increased mutanolysin yield.
    • Contributes to the understanding of microbial metabolism and oxygen requirements in fermentation processes.