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Updated: Jul 11, 2026

Identification and Analysis of Mouse Erythroid Progenitors using the CD71/TER119 Flow-cytometric Assay
Published on: August 5, 2011
[Activity of selenium-dependent enzymes in erythroid cells of animals in the postnatal period]
1Institute of Agriculture and Animal Biology UAAS, Lviv, Ukraine. 1day@icmp.lviv.ua
Abstract:
The age dynamics of selenium-dependent enzymes glutathione peroxidase and thyroxine-5'-deiodinases type I and II (D1 and D2 respectively) in bone marrow erythroblasts of new-born, 1-, 3-, 5- and 10-day old piglets as well as influences of hormones (thyroxine, cortisol) selenium and iron on enzyme activities were investigated. The enzyme activities in the pig erythroid cells were established to increase after birth. D1 activity increased in erythroblasts of 3-day old piglets, while augmentation of D2 activity was significant in the cells of 10-day old animals. Glutathione peroxidase and thyroxine-5'deiodinase activities in pig erythroblasts decreased under the influence of thyroxine and hydrocortisone in vivo, and increased after injections of sodium selenite. For comparison, activities of 5'-deiodinases in the cells of some other tissues were also investigated.
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