Influence of age and normal plasma fibrinogen levels on flow-mediated dilation in healthy adults
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Published on: June 16, 2014
J D Allen1, J B Wilson, R T Tulley
1Department of Kinesiology and Pennington Biomedical Research Center, Louisiana State University, Baton Rouge 70803, USA.
The American Journal of Cardiology
|September 12, 2000
Abstract:
This study examined the effects of age-associated increases in fibrinogen on brachial artery flow-mediated dilation in 30 healthy nonsmokers. The findings demonstrate an inverse association between normal plasma fibrinogen levels and vascular function (r = -0.56, p = 0.001), suggesting elevated plasma fibrinogen may decrease the artery's responsiveness to certain vasodilatory signals, such as shear stress.

