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Updated: Aug 12, 2026

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
Published on: June 21, 2024
Pathology of renal complications in obesity
1Department of Pathology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
Abstract:
Morphologic changes in massive obesity in both humans and experiment animals are rather limited. Glomerulomegaly is common and often asymptomatic. Frequently, ensuing focal and segmental glomerulosclerosis may well be related to alterations in intraglomerular hemodynamics and may result in heavy proteinuria. Factors for the occurrence of segmental glomerulosclerosis have been assessed in animal models and include the influence of lipids. A consequence of surgical therapy for obesity (ie, jejunoileal bypass) is oxalosis with chronic interstitial nephritis, and this may necessitate a takedown of the bypass.
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