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Hidradenitis suppurativa polyposa.

D A Wrone1, A Landeck, D G Dibbell

  • 1Department of Medicine, University of Wisconsin Hospital and Clinics, Madison 53792, USA.

Pathology, Research and Practice
|September 12, 2000
PubMed
Summary
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Severe hidradenitis suppurativa can cause disfiguring fibrous polyps in the perineum. Pathologic examination is crucial to rule out squamous cell carcinoma in these rare cases.

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition.
  • Severe cases can lead to significant anogenital and vulvar disfigurement.

Observation:

  • A case of severe chronic hidradenitis suppurativa involving the perineum is presented.
  • The patient developed disfiguring fibrous, polypoid lesions over a decade, originating from axillary HS.
  • Clinical presentation included draining sinuses, scars, large pendulous vulvar masses, ridges, and papules.

Findings:

  • Histopathology revealed deep clefts, sinuses, dense fibrous scars, and chronic inflammation.
  • The development of large fibrous polyps in chronic HS is a rare complication.
  • Chronic local lymphedema is a potential contributing factor to polyp formation.

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Implications:

  • This case highlights the rare but significant complication of fibrous polyp development in severe anogenital hidradenitis suppurativa.
  • Accurate pathological assessment is essential to differentiate these lesions from squamous cell carcinoma.
  • Understanding the pathogenesis, potentially involving lymphedema, may inform future management strategies.