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3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
Published on: December 9, 2014
Toxoplasmosis in golden-headed lion tamarins (Leontopithecus chrysomelas) and emperor marmosets (Saguinus imperator)
S Epiphanio1, M A Guimarães, D L Fedullo
1Departamento de Patologia, Faculdade de Medicina Veterinária e Zootecnia, da Universidade de São Paulo, Brazil.
Abstract:
From 1991 to 1995, eight New World nonhuman primates of the family Callitrichidae belonging to the collection of Fundacão Parque Zoologico de São Paulo died of toxoplasmosis. Of the eight affected nonhuman primates, four were Leontopithecus chrysomelas (one male, three females) and four were Saguinus imperator (two males, two females). The most commonly affected organs were the lungs, liver, and lymph nodes, with hemorrhagic and necrotic lesions. Histopathologic examination revealed protozoa that were morphologically consistent with Toxoplasma gondii. Immunohistochemical assays were strongly positive for T. gondii.
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