Related Experiment Video
Updated: Aug 12, 2026

Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents
Published on: June 6, 2018
Erectile dysfunction in general medicine practice: prevalence and clinical correlates
K K Chew1, C M Earle, B G Stuckey
1The Keogh Institute for Medical Research, QEII Medical Centre, Perth, Australia.
Erectile dysfunction (ED) is common, affecting nearly 40% of men surveyed, particularly older individuals and those with chronic conditions. Treatment for ED remains significantly underutilized, with only 11.6% of affected men seeking medical help.
Area of Science:
- Urology
- Andrology
- Public Health
Background:
- Erectile dysfunction (ED) is a prevalent condition, especially in aging populations and individuals with comorbidities like cardiovascular disease and diabetes mellitus.
- Understanding the prevalence and associated factors of ED is crucial for effective public health strategies and clinical management.
Purpose of the Study:
- To determine the prevalence of erectile dysfunction in a large cohort of adult men attending general medical practices.
- To investigate the association of ED with age and common chronic health conditions.
- To assess the rate of treatment seeking among men experiencing ED.
Main Methods:
- A cross-sectional study utilizing questionnaires distributed to 1240 adult male attendees across 62 general medical practices.
- Data collected included self-reported erectile dysfunction (occasional, often, complete), age, and presence of chronic diseases.
- Statistical analysis focused on prevalence rates, age-related trends, and correlations with hypertension, ischemic heart disease, peripheral vascular disease, and diabetes mellitus.
Main Results:
- Overall, 39.4% of participants reported some form of ED, with 18.6% experiencing complete ED.
- The prevalence of complete ED significantly increased with age, from 2.0% in men aged 40-49 to 44.9% in those aged 70-79.
- ED was frequently associated with hypertension, ischemic heart disease, peripheral vascular disease, and diabetes mellitus; 40% of diabetic men aged 60+ reported complete ED.
- Only 11.6% of men with ED had received treatment.
Conclusions:
- Erectile dysfunction is highly prevalent in men attending general practice, with a strong age-dependent increase and significant association with cardiovascular risk factors and diabetes.
- There is a substantial gap in treatment-seeking behavior among men with ED, highlighting a need for increased awareness and intervention.
- Further research into barriers to treatment and effective management strategies for ED in primary care settings is warranted.
Related Concept Videos
Dose-Response Relationship: Potency and Efficacy
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
Angina III: Clinical Manifestations and Assessment
Hypertension III: Clinical Manifestations and Diagnostic Studies

