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Related Experiment Videos

Apical aneurysm and left ventricular hypertrophy.

H N Soufen1, C d Frimm, L A Benvenuti

  • 1Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, 05403-900, Brasil. cardebora@incor.usp.br

Arquivos Brasileiros De Cardiologia
|September 13, 2000
PubMed
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A rare cardiac aneurysm associated with severe biventricular hypertrophy was observed in a patient with hypertension. The findings suggest hypertrophic cardiomyopathy as a potential diagnosis in such cases.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Pathology

Background:

  • Systemic arterial hypertension is a common condition associated with cardiovascular complications.
  • Cardiac hypertrophy, particularly biventricular hypertrophy, can be a consequence of long-standing hypertension.
  • Apical aneurysms are rare cardiac findings, typically associated with specific cardiomyopathies.

Observation:

  • A 59-year-old woman with a 16-year history of controlled hypertension presented with an embolic transient ischemic attack.
  • Echocardiogram and MRI revealed severe biventricular hypertrophy and an apical aneurysm containing a thrombus.
  • Endomyocardial biopsy demonstrated histologic disorganization of myocardial cells.

Findings:

  • The co-occurrence of severe biventricular hypertrophy and an apical aneurysm with thrombus is a rare clinical presentation.

Related Experiment Videos

  • The absence of a direct correlation between blood pressure levels and hypertrophy severity, along with biopsy findings, pointed towards hypertrophic cardiomyopathy.
  • This case challenges the typical understanding of cardiac manifestations in systemic arterial hypertension.

    • Implications:

    • This case highlights the importance of considering hypertrophic cardiomyopathy in patients with unexplained cardiac hypertrophy and aneurysms, even with a history of hypertension.
    • It underscores the role of advanced cardiac imaging and histopathology in diagnosing rare cardiovascular conditions.
    • Further research may elucidate the specific mechanisms linking hypertrophic cardiomyopathy and apical aneurysm formation in hypertensive patients.