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Videomorphometric Analysis of Hypoxic Pulmonary Vasoconstriction of Intra-pulmonary Arteries Using Murine Precision Cut Lung Slices
Published on: January 14, 2014
[Vascular rings as a cause of the respiratory disturbances in children]
J Krzystolik-Ladzińska1, D Wiecek-Włodarska, K Guzikowski
1Kliniki Kardiologii Dzieciecej Slaskiej, Akademii Medycznej w Katowicach.
Insights
Vascular rings, rare causes of airway compression in children, require prompt diagnosis. Early identification through imaging is crucial for effective surgical intervention and improved outcomes in pediatric patients.
Area of Science:
- Cardiology
- Pediatric Surgery
- Radiology
Background:
- Vascular rings are uncommon congenital anomalies causing tracheal and/or esophageal compression in pediatric patients.
- Symptoms often mimic respiratory conditions like asthma, leading to delayed diagnosis.
Purpose of the Study:
- To present a series of pediatric cases with vascular rings.
- To highlight diagnostic methods and surgical outcomes.
- To emphasize the importance of considering vascular rings in unexplained chronic cough.
Main Methods:
- Review of 11 pediatric cases (3 months to 15 years) with various vascular ring types.
- Diagnostic modalities included chest X-ray, echocardiography, bronchoscopy, angiography, and MRI.
- Surgical correction was performed for all identified cases.
Main Results:
- The study included 5 double aortic arch, 1 right aortic arch with left arterial ligament, 2 aberrant right subclavian arteries, and 3 pulmonary artery slings.
- Primary surgical results were good, though one infant experienced fatal respiratory complications post-operatively.
- Ten patients were initially referred from pulmonary departments, often misdiagnosed with asthma.
Conclusions:
- Vascular rings necessitate a high index of suspicion in pediatric cases of unexplained chronic cough.
- Comprehensive diagnostic imaging is essential for accurate identification.
- Timely surgical intervention can lead to favorable outcomes, but vigilance for post-operative complications is required.
Abstract:
Vascular rings are an infrequent cause of tracheal and/or oesophageal compression in infants and children. The authors present 11 cases of vascular rings in children from 3 months to 15 years of age. There were: double aortic arch in 5 cases, right aortic arch with left arterial ligament in 1 case, aberrant right subclavian artery in 2 subjects and pulmonary artery sling in 3 patients. The diagnosis was established on the basis of chest X-ray examination, echocardiographic examination, bronchoscopy, angiography and magnetic resonance imaging. Surgical correction was performed in all patients with good primary results. One infant died after several months after operation because of respiratoty system complications. As many as ten subjects were sent to paediatric cardiology unit from pulmonary departments where for the first time a suspicion of vascular ring existance was undertaken. All of them were previously diagnosed and treated in paediatric hospitals, usually as bronchial asthma. It is stressed that in every case of unexplained chronic coughing it is necessary to perform at least lateral X-ray examination of the chest with contrast in oesophagus.
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