Neoplastic involvement of the CNS in generalized lymphomas

In 49 autopsies on patients with generalized malignant lymphomas a thorough histological examination of the CNS was performed. Isolated neoplastic foci were found in the CNS in 10 cases. It is believed that most of the tumour infiltrations in the CNS as a result of neoplastic transformation of local mesenchymal cells and are not blood-borne metastases.