Hydroxychloroquine ototoxicity in a patient with rheumatoid arthritis
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Updated: Oct 13, 2026

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
Published on: March 16, 2018
U Seçkin1, K Ozoran, A Ikinciogullari
1Department of Physical Medicine and Rehabilitation, Ankara Numune Education and Research Hospital, Turkey. pinarb@ato.org.tr
Abstract:
We report a case of reversible sensorineural hearing loss due to hydroxychloroquine (HQ) treatment. The patient was a 34-year-old woman with 1 year of rheumatoid arthritis (RA). She developed reversible hearing loss after 5 months of HQ treatment. Sensorineural deafness has previously been reported with chloroquine treatment, but this is the first report of ototoxicity associated with HQ in RA.
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