Related Experiment Videos
Automation for genomics, part two: sequencers, microarrays, and future trends.
1Department of Electrical Engineering, Genomation Laboratory, University of Washington, Seattle, Washington 98195-2500, USA. deedee@ee.washington.edu
Genome Research
|September 14, 2000
Summary
Automation in genomics has revolutionized DNA sequencing, increasing human genome data by 43-fold. This review covers current DNA sequencing technologies and future innovations in the field.
Area of Science:
- Genomics
- Molecular Biology
- Bioinformatics
Background:
- Genomic sequencing has experienced exponential growth due to automation.
- The past four years have seen a 43-fold increase in finished human genomic sequences.
- This is the second part of a review on automation in genome sequencing.
Purpose of the Study:
- To provide an overview of automation equipment used in genome sequencing.
- To review available DNA sequencers and array technology.
- To discuss future technologies in genomic sequencing.
Main Methods:
- Review of current automation equipment in genome sequencing.
- Examination of DNA sequencing technologies.
- Analysis of array technology.
- Inclusion of alternate sequencing methods.
Main Results:
- Significant advancements in automation have driven a 43-fold increase in human genomic data.
- Current review covers DNA sequencers and array technology.
- Future technologies such as mass spectrometry, biochips, and single molecule analysis are discussed.
Conclusions:
- Automation is critical for the rapid expansion of genomic sequencing.
- The review highlights current and emerging technologies shaping the future of genomics.
- Continued innovation in automation and sequencing technologies will accelerate genomic discovery.