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Updated: Oct 13, 2026

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

[Transient symptomatic osteoporosis and glucocorticoid therapy: bone scintigraphic and magnetic resonance tomographic

B I Kettner1, J Petersein, S Morgera

  • 1Klinik für Nuklearmedizin, Universitätsklinikum Charité, Medizinische Fakultät der Humboldt-Universität zu Berlin, Deutschland.

Nuklearmedizin. Nuclear Medicine
|September 14, 2000
PubMed
Abstract

No abstract available in PubMed .

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...