Related Experiment Videos
Trisomy 4p and partial monosomy 18q due to paternal translocation t(4;18) (p11; q21.3)
G Thanemozhi1, S T Santhiya, N Chandra
1Department of Genetics, Dr. A.L.M. Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai, India.
Indian Journal of Pediatrics
|September 14, 2000
Abstract:
A carrier status for balanced translocation in either of the parents increases the risk of congenital malformation in the offspring. A case of multiple congenital anomalies in a female newborn was found to be associated with trisomy 4p and partial monosomy 18q as a result of a reciprocal translocation, t(4; 18) (p11; q21.3) in the father. The clinical and cytogenetic findings are compared with characteristic features of trisomy 4p, monosomy 18q and two similar cases reported earlier.