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Related Experiment Videos

Enzymatic dissolution of phytobezoars.

A Stanten, H E Peters

    American Journal of Surgery
    |August 11, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Enzymatic dissolution using papain and cellulase effectively treats gastric phytobezoars. Combining these enzymes offers a safe and complication-free medical approach for bezoar dissolution.

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    Area of Science:

    • Gastroenterology
    • Pharmacology

    Background:

    • Phytobezoars are indigestible concretions in the gastrointestinal tract.
    • Gastric phytobezoars can cause significant morbidity and require effective treatment.

    Purpose of the Study:

    • To review the medical treatment of phytobezoars.
    • To evaluate enzymatic dissolution for gastric pouch bezoars.

    Main Methods:

    • Review of clinical and in vitro studies.
    • Assessment of enzymatic dissolution agents papain and cellulase.

    Main Results:

    • Papain and cellulase demonstrated efficacy in dissolving phytobezoars.
    • Combined enzyme administration targets different bezoar components.
    • No complications were reported with enzymatic treatment in the reviewed cases.

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    Conclusions:

    • Enzymatic dissolution is a viable medical treatment for gastric phytobezoars.
    • Combination therapy with papain and cellulase is recommended for enhanced efficacy.
    • This approach offers a safe alternative for managing phytobezoars.